Required Reading – Startup Genome, Non-Dilutive financing, Premature Scaling, etc.

September 12, 2011

The Startup Genome Report (link) Video interview of super entrepreneur, Elon Musk (link) Zymeworks snags a $187M deal with Merck (link) Premature scaling in Biotech startups (link) Our post on sources of non-dilutive financing – part 1 (link, natbiotech_link)

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Non-Dilutive Financing for the Leverage Startup – Part 1

September 6, 2011

In this post, we will discuss the use of non-dilutive financing to incubate early-stage technologies with commercial potential prior to company formation. This strategy is designed to advance technologies originating from, or based in, an academic environment. In a later post, we will explain how the non-dilutive financing strategy can evolve when the startup company [...]

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Required Reading – Leverage Startup, Tech Bubble, Pitching VCs, Sequencing, etc.

June 16, 2011

Our Leverage Startup Model (here) Steve Blank’s take on the Tech Bubble (here) How to pitch a VC as a biotech startup (here) Steve Burrill’s take on the future of biotech (here) Illumina drops the cost of sequencing (here)

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The “Leverage” Start-Up Model

June 9, 2011

Entrepreneurial professors, recent graduates, or students in the life sciences who would like to translate their research into a biotech start-up have the potential to de-risk nascent technology and provide the foundation for a company by using a capital-efficient, non-dilutive operating model we term the “leverage” start-up. This model was developed in response to an [...]

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Required Reading – Quantum Computers, Early Stage Biotech, HIV/Aids, etc.

May 30, 2011

D-Wave Systems sells the first quantum computer (link) The challenges of valuing early stage biotech companies (link) Good overview of the status of HIV/AIDS (link) Accelerator Corp. start new immuno – cancer company (link) The $800 billion payoff of sequencing the human genome (link)

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Web & Social Information Tools for Biotechnologists

May 19, 2011

This post was co-written by Euan Ramsay. The quantity of information accessible via the web can be overwhelming, but through judicious use of free web-based tools a strategy for managing content can be devised. In our experience, biotech entrepreneurs have been slower to adopt these tools than their high-tech cousins. Therefore, this is the first in [...]

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Require Reading – Eric Schmidt, Charles Rivers Ventures, Intellectual Ventures, etc.

May 7, 2011

McKinsey & Co Interviews Google ex-CEO Eric Schmidt (link) Charles Rivers Ventures makes a big bet on patent firm, Intellectual Ventures (link) Fighting off Pharma’s Demise: Burrill & ex-Genentech COO, Myrtle Potter (link) Speed up sequencing, win $1,000,000. Really. (link) Pacific Biosciences starts shipping. (link)

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Implications of Financing Your Biotechnology Start-up

May 4, 2011

Starting a biotechnology company requires thoughtful strategies for the development of your product, and for your intellectual property portfolio, team, and many other areas. One such key aspect is your financing strategy. Deciding on what types of capital to raise and how much financing is required has major implications for the type of business you [...]

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Required Reading – Secondary Markets, Slowing Drug Growth, Gates, Startup Mergers, etc.

April 29, 2011

Barry Silbert discusses new secondary markets for private companies and other alternative assets (link) Burrill Report – growth in drug sales slows (link) Gates Foundation funding many ‘Out of the Box’ ideas (link) Growing your biotech startup through mergers (link) Academic biases and Biotech failures (link)

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Pacific Biosciences – An Inside Look

April 26, 2011

Pacific Biosciences is an interesting entrant in the next wave of DNA sequencing companies.  Over the past few years they have pushed the envelope in sequencing technology by combining impressive advances in nanofabrication, photonic detection systems, and sequencing reactions to create a single molecule realtime (SMRT) sequencing instrument.  Their recent financial docs give a good [...]

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